Bioactive Prenyl- and Terpenyl-Quinones/Hydroquinones of Marine Origin †
نویسندگان
چکیده
منابع مشابه
Bioactive Dehydrotyrosyl and Dehydrodopyl Compounds of Marine Origin
The amino acid, tyrosine, and its hydroxylated product, 3,4-dihydroxyphenylalanine (dopa), plays an important role in the biogenesis of a number of potentially important bioactive molecules in marine organisms. Interestingly, several of these tyrosyl and dopa-containing compounds possess dehydro groups in their side chains. Examples span the range from simple dehydrotyrosine and dehydrodopamine...
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Non-communicable diseases (NCD) are the leading cause of death and disability worldwide. The four main leading causes of NCD are cardiovascular diseases, cancers, respiratory diseases and diabetes. Recognizing the devastating impact of NCD, novel prevention and treatment strategies are extensively sought. Marine organisms are considered as an important source of bioactive peptides that can exer...
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In recent years, the search for novel natural compounds with bioactive properties has received a remarkable boost in view of their possible pharmaceutical exploitation. In this respect the sea is entitled to hold a prominent place, considering the potential of the manifold animals and plants interacting in this ecological context, which becomes even greater when their associated microbes are co...
متن کاملBioactive marine natural products
Bioactive marine natural products can be defined as biologically active products, both secondary metabolites as well as enzymes, lipids and heteropolysaccharides derived from marine sources. Marine natural products have been found to be an important source of drugs and drug leads. These natural products are secondary metabolites and enhance survival fitness and may serve as chemical weapons use...
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Recent results in the chemistry of bioactive marine products are presented. Concerning the cytotoxic a-carbolines : grossularins A and B, the mechanism of the toxicity using supercoiled DNA and synthesis of the imidazolo-a-carboline moiety are presented. In the polysulfur compounds series, the structure of lissoclinotoxin B is proposed as well as a new synthesis of pentathiepins. Novel sesquite...
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ژورنال
عنوان ژورنال: Marine Drugs
سال: 2018
ISSN: 1660-3397
DOI: 10.3390/md16090292